A review on chitosan nanoparticles applications in drug delivery

Autor:	Sandeep Waghulde, Namrata S Shirsat, Sheetal G Roy, Mohan K. Kale, Ashish C Mishra
Rok vydání:	2018
Předmět:	0301 basic medicine Drug Low toxicity media_common.quotation_subject Drug delivery to the brain Nanoparticle Nanotechnology Chitosan nanoparticles Chitosan 03 medical and health sciences chemistry.chemical_compound 030104 developmental biology chemistry Chitin Drug delivery media_common
Zdroj:	Journal of Pharmacognosy and Phytochemistry. 7:01-04
ISSN:	2278-4136 2349-8234
DOI:	10.22271/phyto.2018.v7.isp6.1.01
Popis:	Chitosan is a polymer naturally obtained by deacetylation of chitin. It is a polymer which is biodegradable and biocompatible regarded as safe for human dietary use and also approved for wound dressing applications. Because of their better stability, low toxicity, simple and mild preparation method and providing versatile routes of administration, chitosan nanoparticles have gained more attention as drug delivery carriers. Nanoparticles (NP) are prepared with chitosan and its derivatives possess a positive surface charge and mucoadhesive properties such that can adhere to mucus membranes and release the drug payload in a sustained release manner. Their sub-micron size is suitable for various applications in non-parenteral drug delivery for the treatment of cancer, gastrointestinal diseases, pulmonary diseases, drug delivery to the brain and ocular infections.
Databáze:	OpenAIRE
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