Importance of ocular electrophysiology in the diagnosis of retinal dystrophies
| Autor: | M. Ramos Jiménez, C. Menéndez-de-León, E. Jiménez-López, M.J. Morillo-Sánchez, E. Gutiérrez-Sánchez, M.J. Díaz-Granda, E. Rodríguez-de-la-Rúa-Franch, B. Ponte-Zuñiga, A. Gómez-Escobar, F.B. Domínguez-Serrano |
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| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Not evaluated Pediatrics medicine.medical_specialty Referral business.industry Retrospective cohort study General Medicine Disease medicine.disease Optic neuropathy 03 medical and health sciences 030104 developmental biology 0302 clinical medicine Retinitis pigmentosa 030221 ophthalmology & optometry medicine Medical diagnosis business Retinal Dystrophies |
| Zdroj: | Archivos de la Sociedad Española de Oftalmología (English Edition). 94:160-164 |
| ISSN: | 2173-5794 |
| DOI: | 10.1016/j.oftale.2018.12.007 |
| Popis: | Background and objective The diagnosis of retinal dystrophies is complex and is based on complete ophthalmological study, genetic study and electrophysiological studies (EPS). In this study, we intend to evaluate the role of electrophysiological and medical tests in the diagnosis of retinal dystrophies. Material and methods A retrospective observational study was conducted on 50 selected patients that attended the Neurophysiology Department of the University Hospital Virgen Macarena. An analysis was made of the variables that included, gender, age, referral hospital, reason for which the EPS was requested, applied EPS, genetic study, presumed diagnosis, and definitive diagnosis after EPS. A classification system was subsequently developed, which gives each case a value between 0 and 2, depending on the contribution of the electrophysiological tests to the final diagnosis. Results The mean age was 44.34 ± 18.03 years (60% women). Retinitis pigmentosa (24%), optic neuropathy (12%), and Stargardt's disease (8%) were the most frequent diagnoses. The EPS modified the presumed diagnosis in 48% of the cases, confirmed the diagnosis in 44%, and did not provide any useful information in 8%. The contribution of the EPS was greater in patients seen in the HUVM and when requested by findings in the examination (p = .001). The false positives in the diagnosis of retinal dystrophy were 60% in patients not evaluated by the University Hospital Virgen Macarena. Conclusions Electrophysiological test and specialized management of patients with retinal dystrophies play an important role in the diagnosis of these conditions. |
| Databáze: | OpenAIRE |
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