ChemInform Abstract: Design, Synthesis and Cleaving Activity of an Abiotic Nuclease Based on a Manganese(III) Porphyrin Complex Bearing Two Acridine Moieties

Autor:	Bernard Meunier, Cathy Drexler, Geneviève Pratviel, Mir Wais Hosseini
Rok vydání:	2010
Předmět:	Abiotic component Nuclease biology Acridine derivatives chemistry.chemical_element General Medicine Manganese Porphyrin Combinatorial chemistry chemistry.chemical_compound chemistry Cleave Acridine polycyclic compounds biology.protein DNA
Zdroj:	ChemInform. 29
ISSN:	1522-2667 0931-7597
DOI:	10.1002/chin.199845159
Popis:	The synthesis of meso-5,15-bis(m-aminophenyl)porphyrin bearing two acridine derivatives and of its manganese(III) complex was achieved; in the presence of oxygen atom donors, the metalloporphyrin was shown to cleave double-stranded DNA.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a5ce63c559b08b58e0cc8d1fe926a662 https://doi.org/10.1002/chin.199845159 Zobrazit plný text záznamu Plný text