Laparoscopic peritoneal cytology in the staging of pancreatic and periampullary cancer
| Autor: | T. G. John, E. McGoogan, Stephen J. Wigmore, O. J. Garden, David Carter, Simon Paterson-Brown |
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| Rok vydání: | 1999 |
| Předmět: |
medicine.medical_specialty
Hepatology medicine.diagnostic_test Peritoneal cytology business.industry General surgery Gastroenterology Positive Cytology medicine.disease people.cause_of_death Metastasis Pancreatic cancer Cytology Periampullary cancer Medicine Radiology business people Laparoscopy Prospective cohort study |
| Zdroj: | HPB. 1:13-20 |
| ISSN: | 1365-182X |
| Popis: | Background Peritoneal cytology may be useful in the preoperative assessment of patients with pancreatic cancer. Method A prospective study was undertaken to evaluate the contribution of peritoneal cytology performed during staging laparoscopy in 46 patients with pancreatic or periampullary cancer. Results Laparoscopic peritoneal cytology was positive for the presence of malignant cells in seven patients (15%). All seven patients with positive peritoneal cytology had laparoscopic evidence of tumour unresectability. Negative peritoneal cytology results were obtained in 39 patients, 13 of whom were deemed to have resectable tumours. The median cumulative survival at 6 months was 8% for patients with positive cytology, compared with 71% for those with negative cytology. Discussion Positive peritoneal washings are an indicator of advanced disease and may be a useful adjunct to staging laparoscopy in the detection of patients with unresectable tumours. |
| Databáze: | OpenAIRE |
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