Synthesis, characterization and antifungal activity of copper (II) complexes of sterically hindered o-diphenol derivatives
| Autor: | V. N. Povalishev, G. K. Glushonok, N.P. Osipovich, T.V. Koval’chuk, V. L. Sorokin, G. I. Polozov, A.A. Chernyavskaya, N.V. Loginova, Oleg I. Shadyro, R.A. Zheldakova |
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| Rok vydání: | 2006 |
| Předmět: |
Steric effects
Mucor Antifungal biology Stereochemistry medicine.drug_class Aspergillus niger chemistry.chemical_element biology.organism_classification Medicinal chemistry Copper Inorganic Chemistry Acetic acid chemistry.chemical_compound chemistry Materials Chemistry medicine Physical and Theoretical Chemistry Penicillium lividum Botrytis cinerea |
| Zdroj: | Polyhedron. 25:3603-3610 |
| ISSN: | 0277-5387 |
| DOI: | 10.1016/j.poly.2006.07.015 |
| Popis: | Cu (II) complexes with 3,5-di( tert -butyl)-1,2-benzenediol ( I ), 4,6-di( tert -butyl)-1,2,3-benzentriol ( II ) and sulfur-containing sterically hindered o -diphenol derivatives such as 4,6-di( tert -butyl)-3-(2-hydroxyethylsulfanyl)-1,2-benzenediol ( III ) and 2-[4,6-di( tert -butyl)-2,3-dihydroxyphenylsulfanyl]acetic acid ( IV ) have been synthesized and characterized by means of elemental analysis, TG/DTA, FT-IR, ESR, XPS, XPD and conductivity measurements. Antifungal activities of these ligands and their respective Cu (II) complexes have been determined against Aspergillus niger , Fusarium sp. , Penicillium lividum , Mucor sp. and Botrytis cinerea . Most of the compounds (both the free ligands and the complexes) exert pronounced antifungal activities (RI ⩾ 70%), and virtually all of them (apart from the Cu(L II ) 2 complex) have the highest inhibitory properties (RI = 100%) against B. cinerea . |
| Databáze: | OpenAIRE |
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