Vacunación frente a la gripe estacional en las personas mayores. Evaluación de la vacuna adyuvada: Informe de posicionamiento
| Autor: | Norberto Moreno Villajos, José Antonio López Trigo, Rosa López Mongil, Primitivo Ramos Cordero, Alberto Mariano Lázaro, Gloria Mato Chaín |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Aging medicine.medical_specialty business.industry Mortality rate Public health Immunogenicity 030106 microbiology Medicine (miscellaneous) Literature based Vaccination 03 medical and health sciences 0302 clinical medicine Economic assessment Environmental health Medicine 030212 general & internal medicine Geriatrics and Gerontology Best evidence Older people business |
| Zdroj: | Revista Española de Geriatría y Gerontología. 52:1-14 |
| ISSN: | 0211-139X |
| DOI: | 10.1016/s0211-139x(18)30086-6 |
| Popis: | Flu is a major public health problem, particularly for older people, and creates an important clinical and economic burden. A high mortality rate was reported in Spain during the period 2015 to 2016; 3,101 serious cases were hospitalised with a confirmed diagnosis of flu, of which 11% died (352 cases). Furthermore, financial and health costs are greatly increased by the complications of flu; people aged over 65 years represent approximately 64% of the total costs. Seasonal flu vaccination is the fundamental strategy, as demonstrated by cost-benefit and cost-effectiveness studies. A priority objective is to improve the vaccine's immune response and the search for and inclusion of adjuvants and immunostimulants in vaccines is a major line of research. This positioning report evaluates vaccination for older people and the importance of the adjuvanted vaccine in the elderly in strengthening immunogenicity, by means of a critical review of the literature based on the best evidence available on its immunogenicity and effectiveness, and an economic assessment. |
| Databáze: | OpenAIRE |
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