Disease-free survival pattern in breast cancer patients in India treated in a single institution

Autor:	Kodaganur S. Gopinath, Kumar G Kallur, Shekhar Patil, Nalini K Rao, H P Shashidhar, Basavalinga S. Ajaikumar, Shilpa Prabhudesai, Rao M. Raghavendra, Ramesh Bilimagga S, B.S. Srinath, Ravi B Diwakar
Rok vydání:	2012
Předmět:	Oncology Cancer Research Disease free survival medicine.medical_specialty business.industry Cancer Retrospective cohort study medicine.disease Breast cancer Internal medicine Medicine Single institution business Breast carcinoma
Zdroj:	Journal of Clinical Oncology. 30:e12030-e12030
ISSN:	1527-7755 0732-183X
DOI:	10.1200/jco.2012.30.15_suppl.e12030
Popis:	e12030 Background: This study elucidates data from a 5 year retrospective study evaluating survival rates and prognostic factors in breast carcinoma patients in a private cancer set up in south India. Methods: 1046 patients who were treated between years 2003 to 2008 were analyzed. Clinical data including stage, histopathology type, age, node positivity, treatment plan, chemotherapy regimen, ER/ PR and Her2 Neu status, type of surgery etc were abstracted in a database. Five year disease free survival, local failure free survival and distant failure free survival was calculated using Kaplan Meier survival curves. Log rank mantel hazel tests were used to compare two survival curves. Results: Local recurrence was seen in 4% and distant metastases in 22% of the study sample. 62% of patients presented with early breast cancer (AJCC Stage I, II and IIIA). 85.6% of early and 73.1% of locally advanced breast cancers were disease free at 5 years (p
Databáze:	OpenAIRE
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