Data-Rich Experimentation Enables Palladium-Catalyzed Couplings of Piperidines and Five-Membered (Hetero)aromatic Electrophiles

Autor: Aaron Sather, Theodore A. Martinot
Rok vydání: 2019
Předmět:
Zdroj: Organic Process Research & Development. 23:1725-1739
ISSN: 1520-586X
1083-6160
DOI: 10.1021/acs.oprd.9b00233
Popis: To circumvent a current limitation in palladium-catalyzed C–N cross-coupling methodology, high-throughput experimentation was used to identify a catalyst capable of fusing piperidine-based nucleoph...
Databáze: OpenAIRE