Study on the packed volume-to-void ratio of idealized human red blood cells using a finite-discrete element method
| Autor: | Efstathios Kaliviotis, Eldad Avital, J. Willams, Dong Xu, Chunning Ji, Ante Munjiza |
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| Rok vydání: | 2019 |
| Předmět: |
Normal shape
Partial differential equation Materials science Applied Mathematics Mechanical Engineering Cell number hemic and immune systems Mechanics Container (type theory) 01 natural sciences Discrete element method 010305 fluids & plasmas Void ratio Volume (thermodynamics) Mechanics of Materials hemic and lymphatic diseases 0103 physical sciences 010306 general physics circulatory and respiratory physiology |
| Zdroj: | Applied Mathematics and Mechanics. 40:737-750 |
| ISSN: | 1573-2754 0253-4827 |
| Popis: | Numerical simulations are performed to examine the packing behavior of human red blood cells (RBCs). A combined finite-discrete element method (FDEM) is utilized, in which the RBCs are modeled as no-friction and no-adhesion solid bodies. The volume-to-void ratio of a large number of randomly packed RBCs is clarified, and the effects of the RBC shape, the mesh size, the cell number, and the container size are investigated. The results show that the packed human RBCs with normal shape have a void ratio of 28.45%, which is slightly higher than that of the flat or thick cells used in this study. Such information is beneficial to the further understanding on the geometric features of human RBCs and the research on RBC simulations. |
| Databáze: | OpenAIRE |
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