Conversion of 1,3- into 1,4-dicarbonyl compounds by means of α-phosphoryl sulphides. Total synthesis of dihydrojasmone and methylenomycin B

Autor:	Marian Mikołajczyk, Piotr Łyźwa, S. Grzejszczak
Rok vydání:	1982
Předmět:	Hydrolysis chemistry.chemical_compound chemistry Organic Chemistry Drug Discovery Methylenomycin B Organic chemistry Total synthesis Biochemistry
Zdroj:	Tetrahedron Letters. 23:2237-2240
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(00)87310-4
Popis:	An effective synthesis of 1,4-dicarbonyl systems involving the Horner—Wittig reaction of α-phosphoryl sulphides with the half-protected 1,3-dicarbonyl compounds followed by hydrolysis of the vinyl sulphides formed is described. The total synthesis of dihydrojasmone and methylenomycin B employing this approach is reported.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a525da9dc84815efb72254fa4eb5ab65 https://doi.org/10.1016/s0040-4039(00)87310-4 Zobrazit plný text záznamu