Telomeres and P-element of Drosophila melanogaster contain sequences that replicate autonomously in Saccharomyces cerevisiae
Autor: | A. Ya. Shevelev, B. A. Leibovitch, I. A. Bass, R. B. Khesin, O. N. Danilevskaya, E. V. Kurenova |
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Rok vydání: | 1984 |
Předmět: | |
Zdroj: | Molecular and General Genetics MGG. 197:342-344 |
ISSN: | 1432-1874 0026-8925 |
DOI: | 10.1007/bf00330983 |
Popis: | We have isolated restriction fragments from a “shotgun” collection of Drosophila DNA which function as autonomously replicating sequences (ARS) in Saccharomyces cerevisiae and hybridize with telomeric regions of the 2L, 2R, 4, and X chromosomes. In an independently obtained set of D. melanogaster clones five fragments hybridize in situ with telomeres and a number of internal sites. Two of them also contain ARSs. A Drosophila mobile P-element also possesses ARS activity in yeast. |
Databáze: | OpenAIRE |
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