Telomeres and P-element of Drosophila melanogaster contain sequences that replicate autonomously in Saccharomyces cerevisiae

Autor: A. Ya. Shevelev, B. A. Leibovitch, I. A. Bass, R. B. Khesin, O. N. Danilevskaya, E. V. Kurenova
Rok vydání: 1984
Předmět:
Zdroj: Molecular and General Genetics MGG. 197:342-344
ISSN: 1432-1874
0026-8925
DOI: 10.1007/bf00330983
Popis: We have isolated restriction fragments from a “shotgun” collection of Drosophila DNA which function as autonomously replicating sequences (ARS) in Saccharomyces cerevisiae and hybridize with telomeric regions of the 2L, 2R, 4, and X chromosomes. In an independently obtained set of D. melanogaster clones five fragments hybridize in situ with telomeres and a number of internal sites. Two of them also contain ARSs. A Drosophila mobile P-element also possesses ARS activity in yeast.
Databáze: OpenAIRE