Nitrones and Oxaziridines. LXVII. Intermolecular Cycloaddition of Fused Indolyl Nitrone Ring Systems

Autor:	Donald Craig, Dsc Black, T. A. Wright, Naresh Kumar, R. B. Deb‐Das
Rok vydání:	1993
Předmět:	Indole test chemistry.chemical_classification Biocatalysis Chemistry Supramolecular chemistry General Chemistry Crystal structure Ring (chemistry) Medicinal chemistry Cycloaddition Adduct Nitrone
Zdroj:	Australian Journal of Chemistry. 46:1725
ISSN:	0004-9425
DOI:	10.1071/ch9931725
Popis:	The two dihydro-β-carboline N-oxides (6) and (18) have been prepared by reductive cyclization of 2-acetyl-3-(β- nitroethyl ) indoles. These cyclic nitrones undergo 1,3-dipolar cycloaddition to alkynes to give the cycloadducts (21)-(25). Thermal rearrangement of the adduct (22) gives the indolizino [8,7-b] indole (27) in high yield. The X-ray crystal structure determination of the adduct (24) is reported.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a50855ee0e063a8e9e0097bddf143c35 https://doi.org/10.1071/ch9931725 Zobrazit plný text záznamu