Seasonal variation of triterpenes and phenolic compounds in australianCentella asiatica(L.) Urb

Autor: George Q. Li, Kong M. Li, Ali Alqahtani, Wannit Tongkao-on, Valentina Razmovski-Naumovski, Kelvin Chan
Rok vydání: 2015
Předmět:
Zdroj: Phytochemical Analysis. 26:436-443
ISSN: 0958-0344
DOI: 10.1002/pca.2578
Popis: Introduction Specific triterpenes, phenolic acids and flavonoids in Centella asiatica have been found to be bioactive. Harvesting the plant when these putative bioactive compounds are at their highest concentrations would provide consistency in their chemical profile, thus ensuring the quality and efficacy of derived medicinal products. Objective The aim of the study was to determine the impact of harvesting time on the contents of major triterpenoid and phenolic compounds in C. asiatica. Methodology Australian C. asiatica was collected from a designated area in different months. The principal triterpenes (asiaticoside, madecassoside, asiatic acid and madecassic acid), flavonoid compounds (rutin, quercetin and kaempferol) and chlorogenic acid were quantitatively determined by HPLC-DAD analysis. Results Triterpenoid, kaempferol and chlorogenic acid content showed significant variation (p
Databáze: OpenAIRE