Research progress of response strategies based on tumor microenvironment in drug delivery systems
| Autor: | Naijun Dong, Peng Zhang, Xiumei Lu, Rongxia Wu, Xiu'e Li, Xiaotong Yang |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Tumor microenvironment
Materials science Stimuli responsive Response characteristics Bioengineering 02 engineering and technology General Chemistry 010402 general chemistry 021001 nanoscience & nanotechnology Condensed Matter Physics 01 natural sciences Atomic and Molecular Physics and Optics 0104 chemical sciences Modeling and Simulation Drug delivery Cancer research General Materials Science Nanocarriers 0210 nano-technology |
| Zdroj: | Journal of Nanoparticle Research. 23 |
| ISSN: | 1572-896X 1388-0764 |
| DOI: | 10.1007/s11051-020-05136-7 |
| Popis: | In recent years, nanomedicines have shown tremendous progress in their targeted delivery systems and effective anticancer functions. The targeting, solubility, chemical stability, and degradability of nanocarriers make them widely used. The tumor microenvironment is different from that of normal cells. According to the response characteristics of pH, reducibility, hypoxia, reactive oxygen species, and enzymes, a series of tumor microenvironment stimulation–responsive nanocarrier delivery platforms were constructed. |
| Databáze: | OpenAIRE |
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