Efficacy of chemical disinfectants against SARS-CoV-2 on high-touch surface materials

Autor: Rachael L Hardison, Sarah W Nelson, Rebecca Limmer, Joel Marx, Brian M Taylor, Ryan R James, Michael J Stewart, Sang Don D Lee, Michael Worth Calfee, Shawn P Ryan, Megan W Howard
Rok vydání: 2022
Předmět:
Zdroj: Journal of Applied Microbiology. 134
ISSN: 1365-2672
DOI: 10.1093/jambio/lxac020
Popis: AimsThis study aimed to provide operationally relevant severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) surface disinfection efficacy information.Methods and ResultsThree EPA-registered disinfectants (Vital Oxide, Peroxide, and Clorox Total 360) and one antimicrobial formulation (CDC bleach) were evaluated against SARS-CoV-2 on material coupons and were tested using Spray (no touch with contact time) and Spray & Wipe (wipe immediately post-application) methods immediately and 2 h post-contamination. Efficacy was evaluated for infectious virus, with a subset tested for viral RNA (vRNA) recovery. Efficacy varied by method, disinfectant, and material. CDC bleach solution showed low efficacy against SARS-CoV-2 (log reduction ConclusionsEfficacy depends on surface material, chemical, and disinfection procedure, and suggests that mechanical wiping alone has some efficacy at removing SARS-CoV-2 from surfaces. We observed that disinfectant treatment biased the recovery of vRNA over infectious virus.Significance and Impact of StudyThese data are useful for developing effective, real-world disinfection procedures, and inform public health experts on the utility of PCR-based surveillance approaches.
Databáze: OpenAIRE