ChemInform Abstract: Synthesis of 4-Aryl-1-(4-methylpiperazin-1-yl)phthalazines by Suzuki-Type Cross-Coupling Reaction

Autor:	Camille G. Wermuth, Yveline Rival, Isabelle Parrot, Sébastien Guery
Rok vydání:	2010
Předmět:	chemistry.chemical_compound chemistry Nucleophilic aromatic substitution Aryl Nanotechnology General Medicine Medicinal chemistry Coupling reaction Phthalazines
Zdroj:	ChemInform. 32
ISSN:	1522-2667 0931-7597
DOI:	10.1002/chin.200133171
Popis:	Starting from the commercially available 1,4-dichlorophthalazine, a series of 4-aryl-1-(4-methylpiperazin-1-yl)phthalazines was prepared with good yields and under mild conditions by means of a nucleophilic aromatic substitution and a palladium-catalyzed Suzuki cross-coupling.
Databáze:	OpenAIRE
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