| Autor: |
L. Witherow, Ian D. Wilson, K. Longdon, R. J. Ruane, T. D. Spurway |
| Rok vydání: |
1991 |
| Předmět: |
|
| Zdroj: |
Journal of Chromatography A. 553:497-501 |
| ISSN: |
0021-9673 |
| DOI: |
10.1016/s0021-9673(01)88521-6 |
| Popis: |
The preparation of a two-phase “Pirkle” modified amino-bonded thin-layer chromatography (TLC) plate for enantiomer separation is described. The plate was prepared by partially immersing a commercially prepared aminopropyl high-performance TLC plate in a solution of the chiral selector N-(3,5-dinitrobenzoyl)- l -leucine. The portion of the plate modified with the chiral selector was used to separate the enantiomers of the model compounds 2,2,2 -trifluoro -(9-anthryl)ethanol and 1,1′-binaphthol. The separated enantiomers were then eluted, using continuous development onto the unmodified portion of the plate. The absence of the chiral selector on this segment of the phase allowed the detection of the separated enantiomers by fluorescence quenching. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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