Differentiation Between Psoriatic Arthritis And Rheumatoid Arthritis: A Biochemical And Statistical Analysis Of Fingernail Amino Acids
| Autor: | John M. H. Moll, Mavis S. Greaves, Nicholas R. J. Fieller |
|---|---|
| Rok vydání: | 1979 |
| Předmět: |
chemistry.chemical_classification
medicine.medical_specialty integumentary system business.industry Immunology Arthritis General Medicine medicine.disease Dermatology Amino acid Psoriatic arthritis medicine.anatomical_structure Rheumatology chemistry Psoriasis Rheumatoid arthritis Nail (anatomy) medicine Immunology and Allergy Statistical analysis Differential diagnosis skin and connective tissue diseases business |
| Zdroj: | Scandinavian Journal of Rheumatology. 8:33-38 |
| ISSN: | 1502-7732 0300-9742 |
| DOI: | 10.1080/03009747909105331 |
| Popis: | The differentiation between psoriatic arthritis and rheumatoid arthritis can be clinically difficult if there is no manifest psoriasis of skin or nail. In order to clarify this diagnostic problem, the amino acid patterns in seventy-five psoriatic and non-psoriatic nails have been studied. Using gas--liquid chromatographic techniques and discriminant analysis, a high degree of differentiation (96%) has been established between the normal looking nails of patients with psoriatic arthritis and those with rheumatoid arthritis. This biochemical/statistical approach to the fingernail enhances diagnosis in difficult clinical problems, particularly where there are no overt manifestations of psoriasis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|