Novel Bu4N+Br− catalyzed one-pot multi-component synthesis of 2-amino nicotinonitriles in aqueous medium
Autor: | P. Shanthan Rao, Banda Narsaiah, C. Kurumurthy, T. Yakaiah, R. Naresh Kumar |
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Rok vydání: | 2013 |
Předmět: | |
Zdroj: | Research on Chemical Intermediates. 41:3193-3199 |
ISSN: | 1568-5675 0922-6168 |
DOI: | 10.1007/s11164-013-1424-5 |
Popis: | An efficient single-pot strategy for 2-amino nicotinonitrile derivatives 5 has been developed by multi-component reaction of arylaldehydes 1, methylketones 2, malononitrile 3, and ammonium acetate 4 using tetrabutyl ammonium bromide as catalyst in aqueous medium. |
Databáze: | OpenAIRE |
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