Novel Bu4N+Br− catalyzed one-pot multi-component synthesis of 2-amino nicotinonitriles in aqueous medium

Autor: P. Shanthan Rao, Banda Narsaiah, C. Kurumurthy, T. Yakaiah, R. Naresh Kumar
Rok vydání: 2013
Předmět:
Zdroj: Research on Chemical Intermediates. 41:3193-3199
ISSN: 1568-5675
0922-6168
DOI: 10.1007/s11164-013-1424-5
Popis: An efficient single-pot strategy for 2-amino nicotinonitrile derivatives 5 has been developed by multi-component reaction of arylaldehydes 1, methylketones 2, malononitrile 3, and ammonium acetate 4 using tetrabutyl ammonium bromide as catalyst in aqueous medium.
Databáze: OpenAIRE