Synthesis of 3-arylindole derivatives from nitroalkane precursors

Autor: Veerababurao Kavala, Yu Wen Chen, Chun Wei Kuo, Lyu Lin, Ashok Konala, Chia Yu Huang, Tang Hao Yang, Ching Fa Yao
Rok vydání: 2016
Předmět:
Zdroj: RSC Advances. 6:96049-96056
ISSN: 2046-2069
Popis: 3-Arylindole derivatives were synthesized by Cu(I) catalysed intramolecular Ullmann coupling of 2-bromoarylaminoalkanes. 2-Bromoarylaminoalkanes were synthesized from 2-bromoarylnitroalkanes, which in turn prepared through AlCl3-mediated Friedel–Crafts alkylation of bromo-substituted β-nitrostyrenes and arenes.
Databáze: OpenAIRE