Dopamine β hydroxylase humaine et bovine. Activité vis à vis de la dopamine et de la méthoxytyramine
| Autor: | Claude Bohuon, F Guerinot |
|---|---|
| Rok vydání: | 1968 |
| Předmět: |
chemistry.chemical_classification
medicine.medical_specialty Biochemistry (medical) Clinical Biochemistry Dopamine beta-monooxygenase General Medicine medicine.disease Biochemistry Pheochromocytoma chemistry.chemical_compound Endocrinology Enzyme Biosynthesis chemistry Dopamine Internal medicine Neuroblastoma medicine medicine.drug |
| Zdroj: | Clinica Chimica Acta. 19:125-129 |
| ISSN: | 0009-8981 |
| DOI: | 10.1016/0009-8981(68)90197-6 |
| Popis: | The kinetics of dopamine hydroxylase extracted from two human tumors (one pheochromocytoma and one neuroblastoma) are reported. Two substrates have been studied: dopamine (DM) and 3-methoxytyramine (3-MT). The activity of neuroblastoma enzyme on 3-MT is low and the hypothesis of a by-pass in the biosynthesis of noradrenaline (NA) is invalidated. Results with foetal bovine dopamine hydroxylase show no difference from those with bovine adult enzyme. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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