THYROTROPIC HORMONE AND FLUORINE ACTIVITY

Autor:	Robert H. Wilson, Windsor C. Cutting, Floyd DeEds
Rok vydání:	1940
Předmět:	Pituitary gland medicine.medical_specialty Chemistry Thyroid Stimulation Subcutaneous injection Endocrinology medicine.anatomical_structure Anterior pituitary Thyrotropic cell Internal medicine Toxicity medicine Hormone
Zdroj:	Endocrinology. 26:1053-1056
ISSN:	1945-7170 0013-7227
DOI:	10.1210/endo-26-6-1053
Popis:	IN AN EARLIER PAPER Wilson and DeEds (I) called attention to the synergistic action of orally administered thyroid on the production of bleached rat incisors by fluorine, and briefly reviewed the claims of other authors relative to a relation ship between the thyroid gland and fluorine toxicity. At that time the observations of Wilson and DeEds were correlated with those of Karnofsky and Crpnkite (2) on the effect of thyroxin on eruption of teeth in newborn rats. The present paper deals with the relationship of the anterior pituitary to fluorine toxicity as manifested by an increased susceptibility to the bleaching action of ingested fluorine on rat incisors produced by the daily injection of thyrotropic hormone. Earlier observations on the relationship of the pituitary gland to fluorine toxicity havebeen made by Cristiani (3) and by Phillips, Lamb and coworkers (4, 5, 6). Cristiani reported macroscopic changes in the hypophysis
Databáze:	OpenAIRE
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