Highly effective antibacterial activity of lithium-doped magnesium oxide particles synthesized by the microwave-assisted hydrothermal route

Autor: Qizhe Tian, Guiling Ning, Siqi Zhang, Junwei Ye, Jianchu Zhong, Lei Shi, Wenjie Yuan
Rok vydání: 2020
Předmět:
Zdroj: Powder Technology. 371:130-141
ISSN: 0032-5910
DOI: 10.1016/j.powtec.2020.05.031
Popis: Nanocrystalline magnesium oxide with different lithium doping molar contents were prepared by a microwave-assisted hydrothermal route to improve their antibacterial activity. The as-prepared MgO and Li-doped MgO possess the co-existing structure of nanometer flakes and nanometer particles with the diameter ranged from 50 to 150 nm. The antibacterial effect of Li-doped MgO against Escherichia coli and Staphylococcus aureus was tested by the minimum inhibitory concentration test and colony counting method. It was found that the doping of Li significantly improved the antibacterial activity of MgO. Among the different lithium doping molar contents of MgO, the bactericidal rate of the 3 mol% Li-doped MgO could reach to 99.9% at the concentration of 600 μg/mL, showing the best antibacterial efficiency. The antibacterial mechanism was also investigated. This work establishes guidelines on structural regulation and improvement of MgO antibacterial properties.
Databáze: OpenAIRE