Azathioprine Treatment in Systemic Lupus Erythematosus: A Double Edged Sword

Autor: Jia XIA, Xiao SU, Wei-wei CHEN, Li-qun HE
Rok vydání: 2015
Předmět:
Zdroj: IIUM Medical Journal Malaysia. 14
ISSN: 2735-2285
1823-4631
DOI: 10.31436/imjm.v14i2.424
Popis: Extremely severe pancytopenia induced by low dosage of azathioprine in systemic lupus erythematosus patients is rare. A 40-year-old Chinese female was diagnosed with systemic lupus erythematosus. She suffered worse erythema, oral ulceration, raised erythrocyte sedimentation rate and high anti-dsDNA in August 2013. Then she was initiated on oral azathioprine 50mg/d and extremely severe pancytopenia was seen in September 2013. She was recovered by a series of treatments. Regular monitoring of blood counts is highly recommended to reduce the possible serious myelosuppression induced by azathioprine.
Databáze: OpenAIRE