Cyanomethylative cyclization of unactivated alkenes with nitriles for the synthesis of cyano-containing ring-fused quinazolin-4(3H)-ones

Autor: Han Liu, Zixian Yang, Gao Huang, Jin-Tao Yu, Changduo Pan
Rok vydání: 2022
Předmět:
Zdroj: New Journal of Chemistry. 46:1347-1352
ISSN: 1369-9261
1144-0546
DOI: 10.1039/d1nj05001j
Popis: The synthesis of cyano-containing pyrrolo- and piperidino-quinazolinones was developed using alkyl nitriles through radical cascade addition/cyclization under metal-free conditions.
Databáze: OpenAIRE