ChemInform Abstract: N-Substituted Benzoxazolyl Ureas and Thioureas in Biginelli Reaction Promoted by Trifluoromethane Sulfonic Acid: An Efficient and Convenient Synthesis of Substituted Benzoxazolyl 3,4-Dihydropyrimidine (1H)-(Thio)-ones

Autor:	M. Arjun, M. Saranga Pani, D. Sridhar, K. Srinivas, T. Raviprasad
Rok vydání:	2009
Předmět:	chemistry.chemical_classification Semicarbazides Chemistry Biginelli reaction Condensation Polymer chemistry Thio General Medicine Sulfonic acid Catalysis
Zdroj:	ChemInform. 40
ISSN:	1522-2667 0931-7597
DOI:	10.1002/chin.200952171
Popis:	An efficient synthesis of 3,4-dihydropyrimidine 2 (1 H )-ones and thiones (3,4-DHPMs) core was prepared by one-pot three-component Biginelli condensation and which was catalyzed by trifluoromethane sulfonic acid. The classical Bignelli reaction has been extended by the use of N-substituted benzoxazolyl semicarbazides and thiosemicarbazides and this method has the advantage of excellent yields and short reaction times.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a4a2c3abf42bcd40893e09a9e004a4d1 https://doi.org/10.1002/chin.200952171 Zobrazit plný text záznamu Plný text