| Autor: |
Dmitrijs Bliznuks, Emilija Vija Plorina, Aleksandrs Derjabo, Marta Lange, Ilze Lihacova, Alexey Lihachev |
| Rok vydání: |
2019 |
| Předmět: |
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| Zdroj: |
Clinical and Preclinical Optical Diagnostics II. |
| DOI: |
10.1117/12.2526260 |
| Popis: |
The aim of this study is to develop a novel non-invasive approach for skin cancer (melanoma, basal cell and squamous cell carcinomas) diagnostics by mapping the AF intensity decrease (photo-bleaching) rates under continuous 405 nm LED excitation. For parametric mapping of skin AF intensity decrease rates a sequence of filtered AF imaging under 405 nm LED excitation for 20 seconds at a power density of ~7 mW/cm2 with a frame rate 0.5 fps was recorded and analyzed by cloud-based prototype device. Several clinical cases and potential future applications of the proposed autofluorescence photobleaching rate imaging technique are discussed. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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