Stereoselective total synthesis of (2S,3R)-3-hydroxypipecolic acid

Autor:	Won-Hun Ham, Yong-Shou Tian, Van-Thoai Pham, Chang-Young Oh, Jae-Eun Joo, Yun-Sung Chung, Kee-Young Lee
Rok vydání:	2008
Předmět:	Organic Chemistry Intramolecular cyclization Total synthesis chemistry.chemical_element Oxazoline Key features Catalysis Inorganic Chemistry chemistry.chemical_compound chemistry Organic chemistry Stereoselectivity Physical and Theoretical Chemistry Catalytic hydrogenation Palladium
Zdroj:	Tetrahedron: Asymmetry. 19:318-321
ISSN:	0957-4166
Popis:	A concise, stereocontrolled synthesis of (2 S ,3 R )-3-hydroxypipecolic acid 1 is described. Key features involve diastereoselective oxazoline formation catalyzed by palladium(0) and intramolecular cyclization by catalytic hydrogenation of an oxazoline.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a49c6303f28c7ae8c53a4fb5da4e120f https://doi.org/10.1016/j.tetasy.2008.01.010 Zobrazit plný text záznamu Full Text from ScienceDirect