ChemInform Abstract: Synthesis of Chiral Tetrahydropyrrolo[2,1-b]thiazol-5(6H)-ones

Autor:	Howard C. Smith, Thomas Daniel Aicher, Douglas C. Knorr
Rok vydání:	2010
Předmět:	Amidine Hydrolysis chemistry.chemical_compound chemistry Diastereomer Organic chemistry General Medicine Enantiomer
Zdroj:	ChemInform. 30
ISSN:	1522-2667 0931-7597
DOI:	10.1002/chin.199906122
Popis:	In our investigations of potential hypoglycemic agents,2 it was desired to evaluate optically pure tetrahydropyrrolo[2,1-β]thiazol-5-ones. A novel, practical synthesis of each enantiomer of 1 via formation, separation, and hydrolysis of diastereomeric amidine derivatives is described.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a4933daf90b2ad42e5e485b02c8df6c2 https://doi.org/10.1002/chin.199906122 Zobrazit plný text záznamu Plný text