18 F-FDG PET/CT and contrast-enhanced CT findings of pulmonary cryptococcosis
| Autor: | Tao-Tao Sun, Dong-Lan Luo, Gang Chen, En-Tao Liu, Si-yun Wang, Dan Shao, Shu-Xia Wang |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Fluorodeoxyglucose
Pulmonary cryptococcosis medicine.medical_specialty Lung medicine.diagnostic_test business.industry Standardized uptake value General Medicine medicine.disease 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure Positron emission tomography 030220 oncology & carcinogenesis Cryptococcosis medicine Radiology Nuclear Medicine and imaging Radiology Respiratory system Nuclear medicine business Emission computed tomography medicine.drug |
| Zdroj: | European Journal of Radiology. 89:140-148 |
| ISSN: | 0720-048X |
| DOI: | 10.1016/j.ejrad.2017.02.008 |
| Popis: | Purpose Pulmonary cryptococcosis is an uncommon cause of pulmonary nodules in non-AIDS patients. This study reports the 18 F-fluorodeoxyglucose-positron emission tomography ( 18 F-FDG PET/CT) and contrast-enhanced CT (CE-CT) findings of 42 patients with pulmonary cryptococcosis. Materials and methods A retrospective review of the 18 F-FDG PET/CT and CE-CT findings of 42 patients with histologically proven pulmonary cryptococcosis was conducted. All patients underwent PET/CT and CE-CT in the same session. The CT diagnosis was based on the location, morphological features, and enhancement of lesions. The PET/CT findings were recorded, and clinical data and surgical and histopathological findings were collected. Results The results of the PET scans revealed that 37 (88%) of 42 patients showed higher FDG uptake, and 5 (12%) patients demonstrated lower FDG uptake than the mediastinal blood pool. The maximum standardized uptake value (SUV) of pulmonary cryptococcosis ranged from 1.4 to 13.0 (average: 5.7±3.3, median 4.9). A single nodular pattern was the most prevalent pattern observed and was found in 29 (69%) patients. This pattern was followed by scattered nodular (n=4, 10%), clustered nodular (n=3, 7%), mass-like (n=3, 7%), and bronchopneumonic (n=3, 7%) patterns. The most frequent pattern of immunocompetent patients was the single nodular pattern (29 of 33, 88%). Immunocompromised patients most frequently pattern exhibited mass-like (3 of 9, 33%) and bronchopneumonic (3 of 9, 33%) patterns. Conclusion Pulmonary cryptococcosis most commonly appears as single nodules in immunocompetent patients. Mass-like and bronchopneumonic patterns were common in immunocompromised patients. In 88% of patients, lung lesions showed high FDG uptake, thus mimicking a possible malignant condition. |
| Databáze: | OpenAIRE |
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