Arsenic Metabolism in Mice Carrying a BORCS7/AS3MT Locus Humanized by Syntenic Replacement
| Autor: | John N. Snouwaert, Miroslav Stýblo, Beverly H. Koller, David J. Thomas, Christelle Douillet, Leigh A. Jania, Hisham A. El-Masri |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
inorganic chemicals
Chronic exposure Methyltransferase integumentary system Inorganic arsenic Health Toxicology and Mutagenesis Public Health Environmental and Occupational Health chemistry.chemical_element Locus (genetics) Metabolism Methylation 010501 environmental sciences Biology Pharmacology 01 natural sciences 03 medical and health sciences 0302 clinical medicine chemistry 030212 general & internal medicine Arsenic 0105 earth and related environmental sciences Synteny |
| Zdroj: | Environmental Health Perspectives. 128 |
| ISSN: | 1552-9924 0091-6765 |
| DOI: | 10.1289/ehp6943 |
| Popis: | Background: Chronic exposure to inorganic arsenic (iAs) is a significant public health problem. Methylation of iAs by arsenic methyltransferase (AS3MT) controls iAs detoxification and modifies risk... |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|