Amniotic membrane transplantation for ligneous conjunctivitis in a doberman
Autor: | Deborah Cottrell, Natalie Isaza, Louise O'Leary, Andrew Specht, Maria Kallberg, K. P. Barrie, Caryn E. Plummer |
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Rok vydání: | 2018 |
Předmět: |
medicine.medical_specialty
General Veterinary Ophthalmic examination 040301 veterinary sciences business.industry 04 agricultural and veterinary sciences medicine.disease Doberman Pinscher 0403 veterinary science Transplantation 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure Ophthalmology Cornea Ligneous conjunctivitis 030221 ophthalmology & optometry medicine business Normal range |
Zdroj: | Veterinary Ophthalmology. 21:652-660 |
ISSN: | 1463-5216 |
Popis: | An approximately 2-year-old female Doberman Pinscher was referred for the evaluation of bilateral, chronic proliferative conjunctivitis. Ophthalmic examination revealed bilateral thick, opaque pseudomembranes originating from the conjunctivae that prevented visualization of the cornea and interior structures of the eye. Histopathological findings of biopsies of the pseudomembranes were consistent with ligneous conjunctivitis. Serum plasminogen activity levels were within the normal range. Treatment with topical and systemic anti-inflammatory and immunosuppressive drugs did not improve the conjunctival lesions. The pseudomembranes were surgically excised, and the conjunctival surfaces were reconstructed with amniotic membrane. At final re-examination two years postsurgery, there was no evidence of recurrence of the pseudomembranes. To the authors' knowledge, this is the first reported case of the successful treatment of canine ligneous conjunctivitis with amniotic membrane transplantation. |
Databáze: | OpenAIRE |
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