Body composition in coronary artery disease in KONKAN region of India-Is non- obesity an indicator of Coronary Artery Disease?

Autor:	C. V. Joglekar, Sagar Nanaware, Omkar Anant Dervankar, Amitkumar Bhalerao, Amey Paranjape, Janhavi Deshpande, Pranav Shamraj, Suvarna Netaji Patil, Dnyaneshwar Arjun Jadhav
Rok vydání:	2021
Předmět:	medicine.medical_specialty Ejection fraction business.industry medicine.disease Obesity Body fat percentage Coronary artery disease Internal medicine Diabetes mellitus medicine Lean body mass Cardiology Risk factor Underweight medicine.symptom business
Zdroj:	International Journal of Clinical and Biomedical Research. :11-15
ISSN:	2395-0471 2521-0394
DOI:	10.31878/ijcbr.2021.72.03
Popis:	Background India is witnessing a rising prevalence of non communicable diseases like diabetes, hypertension, coronary artery disease. This is attributed to rapid nutrition and lifestyle transition taking place since last 2 decades. Obesity is a well known independent risk factor but very little information is available about role of leanness (low BMI). We investigated whether non-obesity could be an independent risk factor for Coronary artery disease in a rural clinic in KONKAN. Methods In a cross sectional study we studied body composition of 300 patients (207 men) who underwent Coronary angiography in a rural hospital in KONKAN region. History of diabetes, hypertension and history smoking, tobacco chewing was recorded. Body composition was estimated using bio-impedance analyser. Based on results of coronary angiography, we generated a SYNTAX score derived by number of vessels involved and classified them into groups of severity of coronary artery disease (CAD). Results There were 95 (31 %) diabetes and 189 (63%) hypertensive patients in the sample and 60% of them smoked or chewed tobacco. There were 43 (28 males) patients with SYNTAX score of zero. Among those with coronary artery disease (n=257) increasing severity of CAD was associated with lower body weight, BMI, body fat percentage, and body fat mass and ejection fraction as against positive trend for lean mass and visceral fat. Conclusion BMI, fat mass decreased with severity of CAD while lean mass and visceral fat increased. We observed high proportion of CAD in underweight and lean KONKAN adults. These findings need further investigations
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a450c6eaa5816340cee93a6f20a230f7 https://doi.org/10.31878/ijcbr.2021.72.03 Zobrazit plný text záznamu