Distribution of therapeutic response in asthma control
| Autor: | J. F. Heyse, Theodore F. Reiss, Jonathan M. Edelman |
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| Rok vydání: | 2003 |
| Předmět: | |
| Zdroj: | European Respiratory Journal. 22:568.2-569 |
| ISSN: | 1399-3003 0903-1936 |
| DOI: | 10.1183/09031936.03.00048703a |
| Popis: | From the authors: We are in agreement with G.L. Braunstein's comment that it is important to discuss endpoints that are of clinical relevance to patients and to describe not just average values but results accounting for the entire population. His letter also provides us with an opportunity to rechallenge some of the commonly held assumptions about the clinical interpretation of asthma data and reemphasise the clinical advantages of our approach to describing the response of patients to asthma therapy. We particularly wish to focus on the methodological issues that he has raised. The best definition available of asthma control is from theconsensus guidelines; unfortunately, this description is neither populationbased nor validated. Difficulties have been encountered in efforts to identify and accurately validate the important clinical measures of asthma control, and it remains … |
| Databáze: | OpenAIRE |
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