Comparison of cellular localisation of the Ca2+ -binding proteins calbindin, calretinin and parvalbumin in the retina of four different Macaca species
| Autor: | Nicole Körber, Christian Roski, Andreas Reichenbach, Christiane Langrock, Eberhard Buse, Thomas Pannicke, Gunnar Habermann, Mike Francke |
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| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Nervous system Retina General Veterinary biology General Medicine biology.organism_classification Calbindin Macaque Molecular biology 03 medical and health sciences Rhesus macaque 030104 developmental biology 0302 clinical medicine medicine.anatomical_structure biology.animal biology.protein medicine Tibetan macaque sense organs Calretinin 030217 neurology & neurosurgery Parvalbumin |
| Zdroj: | Anatomia, Histologia, Embryologia. 47:573-582 |
| ISSN: | 0340-2096 |
| Popis: | Ca2+ -binding proteins are differentially expressed in the nervous system; their functional role often remains unclear. This immunohistochemical study aimed at characterising and comparing the expression pattern of the Ca2+ -binding proteins calbindin (Calb), calretinin (Calr) and parvalbumin (Parv) in the retina of four species of macaque monkeys: Macaca fascicularis (cynomolgus macaque), M. mulatta (rhesus macaque), M. thibetana (Tibetan macaque) and M. fuscata (Japanese macaque). Calb was found in cone photoreceptors and in a subset of bipolar cells. Calr was expressed in a subpopulation of amacrine cells. Parv was present in horizontal and ganglion cells. In addition, Muller cells were stained using antibodies against the specific marker cellular retinaldehyde-binding protein (CRALBP). Immunostainings were used for calculation of the density of different cell populations. The expression pattern was similar between the examined species and between retinal regions. |
| Databáze: | OpenAIRE |
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