Generic, Metal-Free Cross-Linking and Modification of Silicone Elastomers Using Click Ligation

Autor:	Ferdinand Gonzaga, Talena Rambarran, Michael A. Brook
Rok vydání:	2012
Předmět:	chemistry.chemical_classification Materials science Polymers and Plastics Organic Chemistry Alkyne Elastomer Silicone Elastomers Inorganic Chemistry Chain length Metal free Chemical engineering chemistry Polymer chemistry Materials Chemistry Click chemistry Surface modification
Zdroj:	Macromolecules. 45:2276-2285
ISSN:	1520-5835 0024-9297
DOI:	10.1021/ma202785x
Popis:	Silicone elastomers are widely used in a variety of biomaterials applications. Their high hydrophobicity can, in some cases, compromise their utility. There exist few convenient, efficient and metal-free processes to introduce hydrophilic groups onto the elastomer surface. We describe the utilization of the metal-free click reaction between azido- and alkynyl-modified silicones to both cross-link and functionalize silicone elastomers. Initial cross-linking at, optionally, reduced or elevated temperatures depending on the alkyne used, results in elastomers whose moduli and tackiness can be controlled by manipulation of cross-link density through use of different chain length constituents: the systematic capping of azides on the azide-rich partner provides a level of control of both cross-linking and residual functionality after cross-linking. The residual azides or alkynes resulting from nonstoichiometric mixing of the starting materials can be used for sequential functionalization of the elastomer as show...
Databáze:	OpenAIRE
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