Approximation of the Dependency of Trace Elements Concentrations in Internal Media upon their Contents in Environment Objects
| Autor: | Faizullin Rashat Iskanderovich, Valiev Vsevolod Sergeevich, Novikova Svetlana Vladimirovna, Tunakova Yulia Alekseevna |
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| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Polynomial Trace (linear algebra) Dependency (UML) Degree (graph theory) Biomedical Engineering Trace element Bioengineering Function (mathematics) Sigmoid function 010501 environmental sciences 01 natural sciences 03 medical and health sciences 030104 developmental biology Content (measure theory) Biological system 0105 earth and related environmental sciences Mathematics |
| Zdroj: | BioNanoScience. 8:288-295 |
| ISSN: | 2191-1649 2191-1630 |
| DOI: | 10.1007/s12668-017-0487-y |
| Popis: | Models that demonstrate the dependency of a trace element content in the internal milieu of an organism upon that in external media objects of the environment were developed to identify dominant factors in ecology-mediated microelement imbalance in a human body. Based on the sets of experimental data obtained on trace element concentrations in the internal milieu (fluids) of a human body (blood) and accumulating media (hair), external fluids (drinking water), and deposit media (soil and snow cover), the degree of approximation of dependencies captured with different models was estimated, with the most adequate ones chosen. Linear, cubic, logistic, sigmoidal, parabolic functions, a polynomial of the fourth and fifth degrees, the Nelder–Mead optimization algorithm, and a Boltzmann function were applied to evaluate the approximation degree by different models. The selection of internal and external media demonstrating the best approximation results is justified. |
| Databáze: | OpenAIRE |
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