Principles of diagnosis, staging and management
| Autor: | A Z S Rohatiner, J M Foran |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
Pathology
medicine.medical_specialty Performance status business.industry Lymphoblastic lymphoma Cytogenetics Disease medicine.disease Lymphoma Trephine biopsy Immunophenotyping immune system diseases hemic and lymphatic diseases Medicine Radiology Nuclear Medicine and imaging Radiology Stage (cooking) business |
| Zdroj: | Imaging. 11:214-229 |
| ISSN: | 1748-8818 0965-6812 |
| DOI: | 10.1259/img.11.4.110214 |
| Popis: | •. The diagnosis of Hodgkin's disease (HD) or non‐Hodgkin's lymphoma (NHL) must be based on a tissue biopsy. Re‐biopsy should be performed at each recurrence when possible.•. The new WHO classification of NHL takes into consideration immunophenotype (90% of lymphomas are B‐cell origin), cytogenetics and molecular biology.•. “Staging investigations”, i.e. CT scans and a bone marrow aspirate and trephine biopsy, should be performed at presentation and at recurrence to determine the extent and distribution of disease.•. Treatment will depend on histological subtype, stage, and the age and performance status of the patient.•. Patients with HD, diffuse large B‐cell NHL and lymphoblastic lymphoma/Burkitt's lymphoma are treated with curative intent. In other subtypes of NHL, recurrence is virtually inevitable with conventional therapy.•. Imaging is essential for staging, assessment of response and in the diagnosis of relapse. Standardized response criteria have been developed, and should be adopted for clinical ... |
| Databáze: | OpenAIRE |
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