Synthesis of 3-[(4-Chloro-phenyl) oxiranyl]thiophen-2-yl-propanone and Their Reactions with Some Nucleophilles for Antiviral Evaluations

Autor:	H. H. Sayed, Mohamed A. Ali
Rok vydání:	2007
Předmět:	Pyrimidine Phenyl isothiocyanate Hydrochloride Organic Chemistry Phosphorus pentasulfide Pyrazole Biochemistry Inorganic Chemistry chemistry.chemical_compound chemistry Thiourea Methyl isothiocyanate Organic chemistry Oxazole
Zdroj:	Phosphorus, Sulfur, and Silicon and the Related Elements. 183:156-167
ISSN:	1563-5325 1042-6507
DOI:	10.1080/10426500701564225
Popis:	Compounds 2, 3, 4, 7, 10, 11, 12 and 13 were formed via the reactions of [3-(4-chlorophenyl)oxiranyl]thiophen-2-yl-propanone with hydrazine derivatives, hydroxyl-amine hydrochloride, thiourea, thiosemicarbazide, carbon disulfide, phenyl isothiocyanate, methyl isothiocyanate and phosphorus pentasulfide, respectively. Pyrimidine derivative 4 was in turn used as precursor for preparation of thiazolopyrimidines 5 and 6. Pyrazolothioamide 7 was treated with D-glucose and arbinose to afford the corresponding hydrazones 8 and 9.
Databáze:	OpenAIRE
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