Vagus nerve stimulation therapy in treatment-resistant depression: A series report

Autor:	Giuseppe Messina, Angelo Franzini, Mario Savino, G. Tisi, Orsola Gambini
Rok vydání:	2014
Předmět:	medicine.medical_specialty Long term follow up business.industry General Neuroscience medicine.medical_treatment Complete remission Poison control Hamilton Rating Scale for Depression General Medicine medicine.disease Surgery Psychiatry and Mental health Neurology medicine Neurology (clinical) business Treatment-resistant depression Depressive symptoms Depression (differential diagnoses) Vagus nerve stimulation
Zdroj:	Psychiatry and Clinical Neurosciences. 68:606-611
ISSN:	1323-1316
DOI:	10.1111/pcn.12166
Popis:	Aim The purpose of this study was to evaluate the efficacy of vagus nerve stimulation (VNS) as a therapeutic option for treatment-resistant depression (TRD), with follow-up periods of 1, 3 and 5 years after VNS surgery. Methods We examined 27 consecutive patients with unipolar TRD. Depressive symptoms were evaluated both at baseline and at follow-up after the surgery by means of the 21-item Hamilton Rating Scale for Depression (HAM-D 21). Results The mean HAM-D preoperative score was 25.6. Twenty-two patients were evaluated after 1 year of treatment, and the mean improvement of the HAM-D score was of 10.3. Five patients (20%) went into complete remission (HAM-D
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a3eadfbaae8fc580d52ae7043f0a41a6 https://doi.org/10.1111/pcn.12166 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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