| Autor: |
Donna Weiss Mellini, Haleem J. Issaq, Thomas E. Beesley |
| Rok vydání: |
1988 |
| Předmět: |
|
| Zdroj: |
Journal of Liquid Chromatography. 11:333-348 |
| ISSN: |
0148-3919 |
| DOI: |
10.1080/01483918809349944 |
| Popis: |
A study of mixed C18/β packings in high performance liquid chromatography was undertaken to evaluate the utility of such phases. The results show that non additive retention times are obtained when a mixed phase column is used while the retention times are additive when two columns, one packed with C18 and the other with β are coupled in a series. A plot of corrected retention times vs % β in C18 gave a non-linear result. This means that the prediction of retention times on a mixed phase column may not be easily done. As a result, in this case, it will be easier to couple two different columns of different selectivities to achieve a difficult separation. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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