Synthesis and properties of derivatives of pyrimidin-5-ylpropanoic acids and 8-aryl-4-methyl- and 4,6-dimethyl-2-phenyl-5,6,7,8-tetrahydropyrido-[2,3-d]pyrimidin-7-ones

Autor:	R. V. Paronikyan, H. M. Stepanyan, G. A. Panosyan, S. G. Chishmarityan, A. A. Harutyunyan
Rok vydání:	2015
Předmět:	Alternative methods chemistry.chemical_compound Pyrimidine chemistry Aryl Organic Chemistry Organic chemistry Amination
Zdroj:	Russian Journal of Organic Chemistry. 51:705-710
ISSN:	1608-3393 1070-4280
DOI:	10.1134/s1070428015050218
Popis:	Proceeding from 3-(4-methyl-6-oxo-2-phenyl-1,6-dihydro-5-pyrimidinyl)propanoic and 2-methylpropanoic acids by successive reactions of chlorination, amination, and heterocyclization 4-amino-substituted pyrimidines were synthesized: 5,6,7,8-tetrahydropyrido[2,3-d]pyrimidine derivatives and 4-methyl-2-phenyl-5,6-dihydrobenzo[4′,5′]imidazo[2′,1′:6,1]pyrido[2,3-d]pyrimidine which we had previously obtained by alternative method. Antibacterial properties of the synthesized compounds were studied.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a3d58fcd4564c010555daaa5fb4fd1c7 https://doi.org/10.1134/s1070428015050218 Zobrazit plný text záznamu Plný text ve formátu PDF