Competitive Reactions in Three-Component System Cationic Colloid–Anionic Liposome–Protein
| Autor: | Olga V. Zaborova, Andrey V. Sybachin, Alexander A. Yaroslavov, A. V. Sandzhieva |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
chemistry.chemical_classification
Liposome Polymers and Plastics Cationic polymerization Albumin 02 engineering and technology Polymer 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences 0104 chemical sciences Microsphere Colloid Adsorption chemistry Polymer chemistry Materials Chemistry Ceramics and Composites Biological media 0210 nano-technology |
| Zdroj: | Polymer Science, Series B. 60:324-330 |
| ISSN: | 1555-6123 1560-0904 |
| DOI: | 10.1134/s1560090418030090 |
| Popis: | The formation of complexes of anionic liposomes (50 nm) and polymer microspheres with grafted polycationic chains with a diameter of 240 nm (spherical polycationic brushes) in a physiological solution at a NaCl concentration of 0.15 mol/L is investigated. Liposomes are quantitatively adsorbed on the surface of brushes; every brush can bind up to 24 intact liposomes. The saturated brush–liposome complex is able to additionally bind negatively charged protein albumin; the excess of protein does not displace liposomes from the complex with brushes. The obtained results are important for understanding the mechanism of formation and functioning of electrostatic multiliposomal containers in biological media containing a high amount of protein. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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