Furanoditerpenes from Arcangelisia flava (L.) Merr. and their antifungal activity

Autor: Wasrin Syafii, Toshisada Suzuki, Mami Maeda, Tamiko Kiyotani, Takeshi Katayama, Kaori Tomita-Yokotani, Sipon Muladi
Rok vydání: 2011
Předmět:
Zdroj: Phytochemistry Letters. 4:333-336
ISSN: 1874-3900
DOI: 10.1016/j.phytol.2011.07.002
Popis: Two furanoditerpenes, 2α,3α-epoxy-2,3,7,8α-tetrahydropenianthic acid methyl ester (1) and 2α,3α-epoxy-2,3-dihydropenianthic acid methyl ester (2) were isolated and identified from the root of Arcangelisia flava (L.) Merr. The configuration of 1 was determined by X-ray crystallographic analysis and two-dimensional NMR. Fibraurin (3), fibleucin (4), 2β, 3α-dihydroxy-2,3,7,8α-tetrahydropenianthic acid-2,17-lactone (5), p-hydroxybenzaldehyde and vanillin were also isolated and identified by NMR and EI-MS or FAB-MS. The 2β, 3α-dihydroxy-2,3,7,8α-tetrahydropenianthic acid-2,17-lactone (5) showed the highest antifungal activity of the isolated five furanoditerpenes against a white-rot fungus (Trametes versicolor) and a brown-rot fungus (Fomitopsis palustris).
Databáze: OpenAIRE