Hemostasis disturbances in patients with acute pancreatitis and the ways of its correction

Autor:	B. Ya. Pidhirnyi, S. М. Chuklin, S. S. Chuklin
Rok vydání:	2015
Předmět:	medicine.medical_specialty business.industry Inflammation Disease medicine.disease Gastroenterology Surgery medicine.anatomical_structure Coagulation Coagulation cascade Hemostasis Internal medicine medicine Acute pancreatitis In patient medicine.symptom Pancreas business
Zdroj:	Medical and Clinical Chemistry. 17
ISSN:	2410-681X
DOI:	10.11603/mcch.2410-681x.2015.v17.i2.4880
Popis:	The literature review imposed the experimental and clinical data on the changes in the hemostatic systemat acute pancreatitis. The reasons of hemostatic disorders and possible ways of its correction were identified.Disturbance in the coagulation is a feature at acute pancreatitis and is associated with disease severity. Theresults of experimental studies in animals and clinical studies suggest that modulation of hemostasis can provide atherapeutic target for the treatment of this disease. Inhibition of the coagulation cascade can prevent intravascularcoagulation and inflammation in the pancreas and distant organs, thereby preventing systemic complications inpatients with acute pancreatitis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a3d074c651ac2762a7f6d7d317a24c60 https://doi.org/10.11603/mcch.2410-681x.2015.v17.i2.4880 Zobrazit plný text záznamu