| Autor: | Evelyne Beraud-Juven, Marcel Crest, Maurice Gola |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
Pharmacology
medicine.medical_specialty Chemistry Multiple sclerosis Organic Chemistry Symptomatic treatment Potassium channel blocker medicine.disease Potassium channel Neurological effects medicine.anatomical_structure Endocrinology Internal medicine Drug Discovery medicine Channel blocker Secretion Axon medicine.drug |
| Zdroj: | Perspectives in Drug Discovery and Design. :333-342 |
| ISSN: | 0928-2866 |
| Popis: | Potassium channels are involved at several stages in inflammatory neuropathies by inducing conduction blocks in demyelinated axons and by taking part in cytokines secretion by activated immunitary cells. Blockers of these channels are therefore potential candidates for the symptomatic treatment of these neuropathies, through their immunosuppressive and neurological effects. This review aims at evaluating the possible therapeutic use of highly selective potassium channel blockers derived from natural toxins. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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