Simulation Approaches to Stretching of Red Blood Cells

Autor: Alžbeta Bohiniková, Katarína Bachratá
Rok vydání: 2019
Předmět:
Zdroj: Bioinformatics and Biomedical Engineering ISBN: 9783030179342
IWBBIO (2)
Popis: In this article we will give brief overview of elastic parameter of our red blood cell (RBC) model. Next we will discuss the importance of calibration of these parameters to get behaviour close to the behaviour of the actual RBC. For this purpose we used a widely known experiment where RBC are stretched by attaching silica beads to their membrane and applying force to these beads. The main focus of this article is how to model this stretching process and more precisely, how to choose between several options available to simulate the optical tweezers stretching. We compared three approaches - “points”, “hat” and “ring”, and based on simulation results selected the “ring” approach. Afterwards we computed working “rings” for different cell discretizations.
Databáze: OpenAIRE