The Heterochromatic ABO Locus May Overlap with the Region Containing Repeats Encompassing Mobile Elements and Stellate Genes on the X Chromosome of Drosophila melanogaster
Autor: | Vladimir A. Gvozdev, Rasheva Vi, Tolchkov Ev, G. L. Kogan, A. M. Popkova |
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Rok vydání: | 2004 |
Předmět: |
Genetics
congenital hereditary and neonatal diseases and abnormalities Euchromatin Heterochromatin Chromosome Locus (genetics) Biology biology.organism_classification biological factors Tandem repeat hemic and lymphatic diseases parasitic diseases Constitutive heterochromatin Drosophila melanogaster X chromosome |
Zdroj: | Russian Journal of Genetics. 40:114-118 |
ISSN: | 1022-7954 |
DOI: | 10.1023/b:ruge.0000016983.38493.93 |
Popis: | A deficiency of certain heterochromatic regions (ABO loci) of various chromosomes dramatically distorts the early embryo development in the progeny of females carrying mutation in the abnormal oocyte (abo) gene, which is located in euchromatin of chromosome 2. One ABO locus (X-ABO) is in X-heterochromatin distal to the nucleolus organizer. A cluster of the Stellate repeats is located in the same heterochromatic block. Deletions of various fragments from distal heterochromatin were tested for the effect on expression of the abo mutation. The X-ABO locus was assigned to X-chromosomal heterochromatin segment h26 and may include repeats consisting mostly of mobile elements and defective Stellate copies. A major part of the regular Stellate tandem repeats proved to be distal of the X-ABO locus. |
Databáze: | OpenAIRE |
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