Response to Letter Regarding Article, 'The Spironolactone, Amiloride, Losartan, and Thiazide (SALT) Double-Blind Crossover Trial in Patients With Low-Renin Hypertension and Elevated Aldosterone-Renin Ratio'
| Autor: | Michael J. Ashby, Kevin Taylor, Morris J. Brown, Susan J. Hood |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Elevated aldosterone
medicine.medical_specialty business.industry Urology medicine.disease Crossover study Hyperaldosteronism Amiloride chemistry.chemical_compound Losartan Endocrinology chemistry Physiology (medical) Internal medicine Renin–angiotensin system Spironolactone Medicine Cardiology and Cardiovascular Medicine business Thiazide medicine.drug |
| Zdroj: | Circulation. 117 |
| ISSN: | 1524-4539 0009-7322 |
| DOI: | 10.1161/circulationaha.107.744250 |
| Popis: | We thank Dr Mulatero and colleagues for their comments on the importance of the Spironolactone, Amiloride, Losartan, and Thiazide (SALT) trial, although the question of whether K+-sparing diuretics protect against glucose intolerance is only now being addressed in a collaborative study by the British Hypertension Society. We acknowledge in turn Dr Mulatero’s recognition, using adrenal vein sampling, that normokalemic primary hyperaldosteronism is not rare. Given, however, the need for this technically demanding investigation to be undertaken in tertiary referral centers, the questions are how common is “not rare” and how high, therefore, the index … |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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