Osteogenic and Regenerative Potential of Free Gingival Graft

Autor:	N. Yu. Matveeva, S. G. Kalinichenko, S. S. Edranov
Rok vydání:	2021
Předmět:	Pathology medicine.medical_specialty Chemistry Mandible Connective tissue General Medicine Bone tissue General Biochemistry Genetics and Molecular Biology Bone remodeling medicine.anatomical_structure Adventitia medicine Alveolar ridge Dental alveolus Fixation (histology)
Zdroj:	Bulletin of Experimental Biology and Medicine. 171:404-408
ISSN:	1573-8221 0007-4888
DOI:	10.1007/s10517-021-05237-w
Popis:	We studied immunolocalization of CD29, CD44, osteocalcin, and TGF-β1 in the bone tissue of the mandible of miniature pigs with extra-bone fixation of a free gingival graft. Three months after surgery, neoosteogenesis foci with high expression of the studied markers were found in the contact area of the free gingival graft with the alveolar bone. The markers were localized in the layer of external circumferential lamellae, on the surface of concentric lamellae of the growing osteons, and in the connective tissue of the Haversian canals. TGF-β1-immunopositive cells predominated in the connective tissue of the Haversian and Volkmann canals and in the adventitia and inner lining of the vascular wall. The established morphochemical patterns of osteogenous cells indicate significant reparative capabilities of a free gingival graft and allows considering it as an effective osteoinductive factor.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a3a42502db3c89e55da5ce1a736f5c1b https://doi.org/10.1007/s10517-021-05237-w Zobrazit plný text záznamu Full text from SpringerLink